The Sabres obviously have their own pick at #2 overall, and their second first rounder, the one they got from the Islanders in the Thomas Vanek trade, will happen at #21. Their other first rounder, the one from St. Louis acquired in the Miller/Ott deal, is set at #25 and will be sent to the Winnipeg Jets per the terms of the Evander Kane trade.
With five picks in the first two rounds, and the #2 overall selection, the Sabres have plenty of ammunition to either move around in the draft, trade for established players (goalie anyone?) or simply continue to stock one of the league's best farm systems.
The full list of Sabres draft picks is below:
#21 (from NYI)
#51 (from NYI)