| Buffalo Sabres (13-10-1, 27pts) | Game #25 | Detroit Red Wings (15-7-1 31pts) |
 | vs. | |
| Date: | December 2, 2011 | Location: | Buffalo, NY |
| Time: | 7:30 p.m. ET | Arena: | First Niagara Center |
| TV: | MSG | SBN Affiliate/ Blog | Winging It In Motown |
| Radio: | WGR (550AM) | Season Series | 0-0 |
| Category | Buffalo Sabres | Detroit Red Wings |
| Goals For | 66 (2.75) | 68 (2.96) |
| Goals Against | 62 (2.58) | 51 (2.22) |
| Shots For | 742 (30.9) | 802 (34.9) |
| Shots Against | 746 (31.1) | 619 (26.9) |
| Power Play | 16/87 - 18.4 (9) | 19/98 - 19.4% (7) |
| Penalty Kill | 78/89 - 87.6% (5) | 69/86 - 80.2% (24) |