| Buffalo Sabres (21-20-5, 47pts) | Game #47 | New York Islanders (14-24-7, 35pts) |
 | vs. |
|
| Date: | January 21, 2011 | Location: | Buffalo, NY |
| Time: | 7:30 p.m. ET | Arena: | HSBC Arena |
| TV: | MSG | SBN Affiliate/ Blog | Lighthouse Hockey |
| Radio: | WGR (550AM) | Season Series | 0-1-0 |
| Category | Buffalo Sabres | New York Islanders |
| Goals For | 123 (2.67) | 108 (2.40) |
| Goals Against | 134 (2.91) | 146 (3.24) |
| Shots For | 1547 (33.6) | 1276 (28.4) |
| Shots Against | 1400 (30.4) | 1473 (32.7) |
| Power Play | 33/176 - 19.2% (12) | 31/177 - 17.5% (18) |
| Penalty Kill | 147/179 - 82.1% (16) | 145/177 - 81.9% (19) |